Harm Reduction Circle, a 501(c)(3) nonprofit based in Irvine, California, leads efforts to combat the opioid crisis through education and evidence-based harm reduction. As a key naloxone distributor in Southern California, we focus on vulnerable populations, conducting street-based outreach in Orange County three to four times weekly. Our impact extends across the western U.S., with large-scale harm reduction services reaching over 9,500 individuals this year, including 4,600 experiencing homelessness. In 2024 alone, we distributed over 56,000 doses of Kloxxado 8mg Nasal Spray, advancing our mission to reduce overdose fatalities and drug-related harm.